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Etoposide Injection Side Effects

There were a number of side effects reported during clinical studies on etoposide injection, including some that are potentially serious. Contact your healthcare provider immediately if you are using this chemotherapy medicine and develop problems like fever, extreme weakness, or persistent diarrhea. Some of the most commonly reported reactions include hair loss, nausea, and reduced appetite.

An Introduction to Side Effects of Etoposide Injection

As with any medicine, etoposide injection (Toposar®) can cause side effects. In fact, most people will experience some type of reaction to this drug. As with other chemotherapy medicines, etoposide injection side effects can be significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with etoposide injection. Your healthcare provider can discuss a more complete list with you.)

Serious Etoposide Injection Side Effects

Some side effects of etoposide injection are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • Sore throat
    • Painful urination
  • Signs of anemia, such as:
    • Extreme weakness or fatigue
    • Pale skin
    • Shortness of breath
    • Dizziness
  • Any unusual bleeding or bruising
  • Mouth or throat sores, ulcers, or blisters
  • Swelling, burning, stinging, pain, or leakage of fluid around your infusion site (the site where you receive your dose)
  • Signs of an allergic reaction, especially while receiving your infusion, such as:
    • Chills
    • Fever
    • A fast heart rate (tachycardia)
    • A rash
    • Hives
    • Itching
    • Swelling of the mouth, tongue, face, lips, or throat
    • Difficulty breathing or swallowing
    • A feeling of tightness in the throat
    • Sudden cough
    • Sweating
    • Chills
    • Fever
    • Dizziness or fainting
  • Loss of vision
  • Signs of liver problems, such as:


    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Upper-right abdominal (stomach) pain
  • Persistent diarrhea or vomiting
  • Burning, tingling, pricking, numbness, or other unusual sensations in the arms, hands, legs, or feet
  • Signs of dehydration, such as:
    • Thirst
    • Dry mouth and lips
    • Lightheadedness
    • Less frequent urination.
The Dirty, Messy Part of BPH

Etoposide Injection Information

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