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Enzalutamide Side Effects

When enzalutamide was given to men during clinical trials, some of the most common reactions included joint pain, fatigue, and diarrhea. Fortunately, most men who use this chemotherapy drug tolerate it fairly well. Serious side effects with enzalutamide are possible, however, and may include problems like blood in the urine or numbness in your legs.


An Introduction to Side Effects of Enzalutamide

Just like any medicine, enzalutamide (Xtandi®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with enzalutamide. Your healthcare provider can discuss a more complete list with you.)

Serious Enzalutamide Side Effects

Some side effects of enzalutamide are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Changes in bowel or urine habits
  • Numbness or weakness in the legs
  • Numbness, tingling, or pricking sensations of the skin
  • Shortness of breath, difficulty breathing, or a cough
  • Blood in the urine
  • Falls
  • Loss of consciousness
  • Seizures
  • Problems thinking clearly
  • Seeing or hearing things that are not real (hallucinations)
  • Signs of infection, such as:
  • Signs of an allergic reaction, such as:
    • Hives
    • Itching
    • Unexplained swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing or swallowing.
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Enzalutamide Drug Information

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