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Clinical Effects

In a clinical study, enzalutamide extended the life of men with prostate cancer that had spread beyond the prostate and was resistant to treatment to lower testosterone levels.
In this study, men given enzalutamide lived a median of 18.4 months after starting treatment. The median is the midpoint, meaning half of the men lived longer than 18.4 months and half did not live for 18.4 months. Men who were given a placebo pill (a sugar pill that does not contain any active ingredients) lived a median of 13.6 months.
All the men in the study had previously been treated with docetaxel.

When and How to Take This Medicine

Some general considerations to keep in mind during treatment with enzalutamide include the following:
  • Enzalutamide comes in the form of a capsule. It is normally taken by mouth once a day. 
  • Try to take your dose at about the same time each day to keep an even level of the drug in your bloodstream.
  • Enzalutamide can be taken with or without food. Try taking it with food if it upsets your stomach.
  • This medication must be swallowed whole; do not open, crush, cut, dissolve, or chew the capsules.
  • For enzalutamide to work properly, it must be taken as prescribed. Do not stop taking this medicine just because you feel better.

Dosing Information for Enzalutamide

The specific dose of enzalutamide your healthcare provider recommends may vary, depending on a few factors, including:
  • How you tolerate the medicine
  • Other medications you are taking.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Enzalutamide Dosage for more information.)
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Enzalutamide Drug Information

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