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Enzalutamide

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
     
  • Ever had a seizure
     
  • Had a brain injury, especially with loss of consciousness
     
  • Had a stroke or "mini-stroke" (transient ischemic attack, or TIA)
     
  • Been told you have an abnormal connection between arteries and veins in the brain (a condition known medically as a brain arteriovenous malformation)
     
  • Brain tumors
     
  • Any allergies, including to foods, dyes, or preservatives.
 
Enzalutamide is not for use in women. However, if you are a woman and your healthcare provider has recommended this medication, let him or her know if you are:
    
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Enzalutamide to learn more, including information on who should not take the drug.)
 

How Does Enzalutamide Work?

Androgens (male sex hormones, such as testosterone) stimulate the growth of prostate cancer. Enzalutamide is known as an androgen receptor inhibitor (also known as an antiandrogen). It works by binding to androgen receptors and preventing testosterone from also binding to the receptor. Enzalutamide is also thought to block the downstream effects of testosterone after it binds to the androgen receptor.
 
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Enzalutamide Drug Information

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