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Emend

Clinical Effects

In studies of Emend to prevent nausea and vomiting due to chemotherapy, it was added to a regimen of two other nausea and vomiting medications: ondansetron (Zofran®) and dexamethasone (Decadron®). People who added Emend to their regimen experienced less vomiting, compared to those taking just ondansetron and dexamethasone. While adding Emend decreased the chance of vomiting, it did not seem to decrease the chance of nausea.
 
Emend was also studied for preventing nausea and vomiting after surgery. It was compared to ondansetron (Zofran). Compared to ondansetron, Emend reduced the chance of vomiting within the first 48 hours after surgery by up to 15.2 percent.
 

When and How to Take Emend

General considerations for when and how to take Emend include the following:
 
  • The medication comes in capsule form. It is taken by mouth, usually one hour before chemotherapy or within three hours before surgery. Surgery patients take just one dose, while chemotherapy patients usually take two more doses (in the next two mornings after the first dose). Emend is also available in an injection (given by IV) that can be used in place of the oral dose for use before chemotherapy.
     
  • Emend can be taken with or without food. However, you may need to have an empty stomach for surgery. Be sure to ask your healthcare provider if you may take the drug with food.
     
  • For the medication to work properly, it must be taken as prescribed.
     

Dosing Information

The dose of Emend your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Whether you are having surgery or chemotherapy
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Emend Dosage for more information.)
 
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Emend Drug Information

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