Side Effects of Diindolylmethane
There are no known side effects of diindolylmethane at this time. Although side effects were not reported in clinical trials or case reports, it does not mean that side effects are not possible with this supplement. If you develop any problems while using diindolylmethane, let your healthcare provider know; it may be a diindolylmethane side effect.
Diindolylmethane (DIM) is a compound naturally formed in the body when cruciferous vegetables (like broccoli and cauliflower) are digested in the human stomach. It is also available as a dietary supplement. At this time, there are no known side effects of diindolylmethane. However, this does not guarantee that diindolylmethane does not cause side effects; it simply means that no diindolylmethane side effects have been reported, either in clinical studies or in case reports.
Case reports are individual reports from healthcare providers about side effects seen in their patients. Most likely, the lack of reported diindolylmethane side effects reflects a lack of studies large enough to find side effects (or a lack of studies that were designed to look for side effects); it probably does not indicate that diindolylmethane really is free of side effects.
Just because diindolylmethane is a natural product of cruciferous vegetable digestion does not mean that it is safe or free of side effects. Taking diindolylmethane alone (without the other components formed during cruciferous vegetable digestion) could change the effects of diindolylmethane, as might taking more diindolylmethane than would normally be consumed through food.
Make sure to tell your healthcare provider if you develop any side effects that you think may be related to diindolylmethane. You should also let your healthcare provider know if you develop something that "just does not seem right" during treatment with diindolylmethane. While it may not be a side effect of diindolylmethane, your healthcare provider will be able to diagnose and treat the problem.