There is currently not enough information available to recommend a safe and effective diindolylmethane dosage for any use. While medications are tested in dose-range studies, dietary supplements are not, leaving only vague "trial and error" information. It is probably best to follow the diindolylmethane dosing guidelines provided with your particular product.
Diindolylmethane (DIM) is a dietary supplement taken for cancer prevention and various other uses. Unlike medications (for which the standard doses have been well established in carefully designed studies), there is less information for determining the best dose for herbal supplements, including diindolylmethane.
With prescription (and non-prescription) medications, researchers establish the most effective and safe doses in special studies, known as dose-range studies. These studies are done early in the development of medications, long before they are ever approved. However, because dietary supplements do not require approval, dose-range studies are rarely performed. Without such studies, only vague "trial and error" information is available.
At this time, there is not enough information available to recommend a safe and effective dose of diindolylmethane for any use. With so little information to guide you in determining an appropriate dose for diindolylmethane, it is reasonable to follow the dosing instructions provided with your particular product (with an understanding that such recommendations probably have very little scientific basis).
Some considerations for people taking diindolylmethane include:
- Since the manufacturing of supplements (such as diindolylmethane) is not closely regulated, it is important to choose a trustworthy manufacturer for diindolylmethane supplements. Your pharmacist can help you find a diindolylmethane supplement from a good manufacturer.
- If you have any chronic health problems or take any prescription medications, it is probably a good idea to check with your healthcare provider before taking diindolylmethane.
- If you are unsure about anything related to your dosage or diindolylmethane dosages in general, please talk with your healthcare provider.