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Dasatinib Side Effects

Common Side Effects

Dasatinib has been studied extensively in clinical trials. In these studies, the side effects that occurred in people taking dasatinib were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
 
In these studies, the most common dasatinib side effects included:
 
  • Fluid retention (edema) -- in up to 35 percent of people
  • Headaches -- up to 33 percent
  • Diarrhea -- up to 31 percent
  • Bleeding -- up to 26 percent
  • Fatigue -- up to 24 percent
  • Nausea -- up to 24 percent
  • Low blood cell counts -- up to 22 percent
  • Skin rash -- up to 21 percent
  • Shortness of breath -- up to 20 percent
  • Muscle pain -- up to 19 percent
  • Fever -- up to 18 percent.
 
Other common side effects, occurring in 1 to 16 percent of people, included:
 
  • Vomiting
  • Infections, including viral, bacterial, and fungal infections
  • Joint pain
  • Abdominal (stomach) pain or swelling
  • Mouth sores, inflammation, or pain (see Mouth and Gum Problems During Chemotherapy)
  • Heartburn or indigestion
  • Constipation
  • Tiredness or weakness
  • Chest pain
  • Chills
  • Itching
  • Hives
  • Hair loss
  • Skin problems, such as dry skin, itching, and eczema
  • Excessive sweating
  • Coughing
  • Tingling, pricking, or numbing sensations of the skin
  • Dizziness
  • Changes in taste
  • Drowsiness
  • Muscle weakness
  • Weight changes
  • Appetite loss
  • Increased heart rate
  • Vision problems, such as blurred vision
  • Increased blood pressure (hypertension)
  • A sudden redness and warmth of the face, neck, and chest (flushing)
  • Insomnia
  • Depression
  • Ringing in the ears.
 
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