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Cometriq Side Effects

Serious Side Effects

Some side effects of Cometriq are potentially serious and should be reported to your healthcare provider right away. These include but are not limited to:
 
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
 
  • Severe or persistent diarrhea
  • Blisters, sores, redness, swelling, pain, or peeling of the skin on the palms of the hands or soles of the feet
  • Ulcers, sores, pain, or swelling in the mouth, especially if it prevents you from eating and drinking
  • Jaw pain or toothache
  • Any abnormal or unusual bleeding or signs of bleeding problems, such as:
    • Coughing up blood
    • Black, tarry, or bloody stools
    • Vomiting blood or vomit that looks like coffee grounds
    • Heavier-than-normal menstrual bleeding in women
 
  • Severe abdominal (stomach) pain
  • Coughing, gagging, or choking when eating or drinking
  • Signs of blood clots, such as:
    • Warmth, swelling, or pain in an arm or leg
    • Shortness of breath
    • Chest pain
 
  • Signs of a stroke, such as:
    • Difficulty seeing, speaking, or walking
    • Confusion
    • Loss of coordination or balance
    • Weakness in your face, arm, or leg
    • A severe headache
 
  • Signs of a heart attack, such as:
    • Chest pain or discomfort
    • Shortness of breath
    • Sweating
    • Nausea
    • Feeling lightheaded or faint
 
  • Wounds that don't heal or heal slowly
  • High blood pressure (hypertension)
  • Swelling of the arms, hands, legs, ankles, or feet
  • Significant weight loss
  • Signs of a serious condition known as reversible posterior leukoencephalopathy syndrome (RPLS), such as:
 
  • Signs of infection, such as:
 
  • Yellowing of the skin or whites of the eyes (jaundice).
 
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