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Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • Received radiation treatment
  • Received other chemotherapy treatment
  • Low white blood cells
  • Low platelets or anemia
  • A history of seizures
  • Ever had a head injury
  • An infection or get infections easily
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Chlorambucil to learn more, including information on who should not take the drug.)

How Does It Work?

Chlorambucil belongs to a group of medicines known as alkylating agents. It works by interfering with DNA replication, a process which is necessary for cells to copy themselves and divide. This causes cell death. The medication also activates a protein that causes cell death by a process known as apoptosis.
While chlorambucil can kill both healthy and cancerous cells, it has a greater effect on cells that are multiplying rapidly. Generally, cancer cells multiply more rapidly than healthy cells and are, therefore, more affected by chlorambucil.
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Chlorambucil Drug Information

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