Important Information for Your Healthcare ProviderYou should talk with your healthcare provider prior to taking this medication if you have:
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Anemia or other blood cell problems
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Casodex and Pregnancy)
- Breastfeeding (see Casodex and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Bicalutamide to learn more, including information on who should not take the drug.)
How Does Bicalutamide Work?Prostate cancer cells grow in response to androgens (male sex hormones). Bicalutamide is an androgen receptor inhibitor (sometimes called an antiandrogen). It works by binding to androgen receptors in the prostate and blocking the effect of naturally occurring androgens. This helps prevent the growth of prostate cancer cells.
Bicalutamide is used in combination with a gonadotropin-releasing hormone (GnRH) agonist medicine, sometimes called a luteinizing hormone-releasing hormone agonist. GnRH agonists reduce the amount of testosterone made by the body. Thus, bicalutamide blocks the action of the remaining testosterone.