Clinical EffectsIn clinical trials, up to 68 percent of people with non-Hodgkin's lymphoma responded to Bexxar treatment. People were said to have responded if some signs of cancer disappeared. All of the people in the clinical trials were previously treated for their non-Hodgkin's lymphoma and did not respond. It is unknown if Bexxar has any effect on survival.
When and How to Receive ItSome general considerations to keep in mind during treatment with Bexxar include the following:
- This medication comes in the form of a liquid that is given as a slow injection into a vein (an intravenous, or IV, infusion).
- You will be given four total infusions on two different days -- two infusions one day, followed by two more infusions on the same day of the week, one to two weeks later.
- It normally takes about 90 minutes to receive your infusions, although your appointment may take longer.
- The infusion will be administered by a healthcare provider in a healthcare setting, such as a hospital or clinic.
- You will be given other medications to protect your thyroid, starting at least 24 hours before your first Bexxar dose, and continuing for 14 days after your last Bexxar dose. You will also be given premedication before your infusions to help prevent infusion reactions. This usually consists of acetaminophen (Tylenol®) and diphenhydramine (Benadryl® and others), or other similar medications.
- For the medication to work properly, it must be used as prescribed. It is important to keep your appointments to receive your doses.
Dosing InformationThe dosage your healthcare provider recommends will vary, based on the following factors:
- Your platelet count (as measured using a simple blood test)
- How much Bexxar is absorbed into your bloodstream after your first two infusions.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Bexxar Dosage for more information.)