Bevacizumab Dosing

Bevacizumab dosing guidelines take various factors into account, such as the type of cancer being treated and the kind of chemotherapy that is also being used, among other things. For example, when treating non-squamous, non-small cell lung cancer, the recommend dose is 15 mg per kg every three weeks. For colorectal cancer, bevacizumab dosing guidelines call for 5 or 10 mg per kg every 14 days.

An Introduction to Bevacizumab Dosing

The dose of bevacizumab (Avastin®) that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your weight
  • Whether you have colon, rectal, or lung cancer
  • The type of chemotherapy you are receiving
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your bevacizumab dose unless your healthcare provider specifically instructs you to do so.
 

Bevacizumab Dosing for Colorectal Cancer

The recommended dose of bevacizumab when treating colon or rectal cancer is either 5 mg or 10 mg per kg (about 2.3 mg to 4.5 mg per pound) given by IV every 14 days. The recommended dose will vary (either 5 or 10 mg per kg) based on the type of chemotherapy you are receiving along with bevacizumab.
 

Bevacizumab Dosing for Lung Cancer

The recommended dose of bevacizumab when treating non-squamous, non-small cell lung cancer is 15 mg per kg (about 6.8 mg per pound) given by IV every three weeks.
 

Bevacizumab Dosage for Breast Cancer, Brain Cancer, or Kidney Cancer

The recommended dose of bevacizumab when treating breast cancer, glioblastoma (a type of brain cancer), or renal cell cancer (a type of kidney cancer) is 10 mg per kg (about 4.5 mg per pound) given by IV every 14 days.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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