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Lymphoma and Bendamustine

Some people who have a certain type of lymphoma may receive bendamustine (Treanda®). This prescription chemotherapy drug is given to adults who have a type of non-Hodgkin's lymphoma (NHL) that has become worse during or within six months of treatment with another medication known as rituximab (Rituxan®).
Non-Hodgkin's lymphomas are a large group of cancers that are categorized based on how quickly they spread and the type of lymphocyte affected -- either B-cells or T-cells. Indolent cancers have a slow-growing course and normally cause fewer symptoms. Indolent NHL can become aggressive. Aggressive NHL is a fast-growing cancer and spreads more quickly throughout the body.
Bendamustine is approved to treat indolent B-cell non-Hodgkin's lymphoma. It works by interfering with DNA replication, which is a process necessary for cells to copy themselves and divide. This causes cell death.
(Click What Is Bendamustine Used For? to learn more about using this drug for lymphoma treatment. This Web selection takes a closer look at this and other approved uses for bendamustine, along with possible off-label uses.)
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