Bendamustine Dosing for Non-Hodgkin's LymphomaThe recommended dosage of bendamustine for the treatment of non-Hodgkin's lymphoma (NHL) is also based on body surface area. The recommended amount is 120 mg per m2 given intravenously over 60 minutes. This dose is given once a day for two days in a row every 21 days. This 21-day period is called a treatment cycle. Bendamustine is given on days one and two of the cycle, followed by 19 days without treatment. The cycle may then be repeated up to eight times.
Your healthcare provider may reduce your amount or recommend a longer break between doses if you experience potentially serious bendamustine side effects, such as low blood cell counts. For example, some people with NHL may be given doses as low as 60 mg per m2.
General Information on Receiving BendamustineSome considerations to keep in mind during treatment with bendamustine include the following:
- Bendamustine comes as a powder that is mixed with sterile water. It is given as a slow injection through a needle into a vein (an intravenous, or IV, infusion) once a day for two days in a row every 21 to 28 days.
- The injection is normally given in a healthcare setting, such as a hospital, infusion center, or a healthcare provider's office. It is given over a 30- to 60-minute period.
- Your healthcare provider may give you other medicine to take before your injection to help prevent certain side effects.
- For the medication to work properly, it must be used as prescribed. It is important to keep your appointments to receive your bendamustine doses.
- If you are unsure about anything related to your dosage, please talk with your healthcare provider or pharmacist.