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Axitinib Side Effects

Although not everyone who takes axitinib will experience problems, most people will develop some type of side effect. Axitinib has been shown to cause potentially serious complications, such as liver problems, infections, or allergic reactions, which require immediate medical treatment. Some of the more commonly reported reactions to this drug include decreased appetite, weakness, and vomiting.

An Introduction to Side Effects of Axitinib

Just like any medicine, axitinib (Inlyta®) can cause side effects. In fact, most people who take axitinib will develop some sort of side effect. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with axitinib. Your healthcare provider can discuss a more complete list with you.)

Serious Axitinib Side Effects

Some side effects of axitinib are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Signs of infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • Sore throat
    • Cough
    • Nausea and vomiting
  • Signs of liver problems, such as:


    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Tiredness or fatigue
    • Pain in the upper-right area of the abdomen (stomach)
  • High blood pressure (hypertension)
  • Redness, blistering, or peeling of the palms of the hands or soles of the feet
  • Difficulty walking, talking, or speaking
  • Weakness or numbness on one side of the body
  • A sudden severe headache
  • Unusual bleeding or bruising
  • Black, tarry, or bloody stools
  • Vomiting blood or vomit that looks like coffee grounds
  • Coughing up blood
  • Sores or ulcers in the mouth
  • Sudden blurred or loss of vision
  • Sudden shortness of breath
  • Extreme fatigue, dizziness, or weakness
  • Unexplained weight loss or gain
  • Feeling cold or hot
  • Hair loss
  • Swelling, pain, or tenderness in a leg
  • Chest pain or pressure
  • Pain in the arm, neck, back, or jaw
  • Wounds that do not heal or appear infected
  • New or worsening abdominal (stomach) pain
  • Confusion or problems thinking
  • Seizures.
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Axitinib Drug Information

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