Anzemet is used for preventing or treating nausea and vomiting in people who are about to have surgery. It can also help prevent these problems in people undergoing chemotherapy. Healthcare providers may also occasionally recommend "off-label" Anzemet uses. For example, using the drug to prevent or treat nausea and vomiting due to other causes is considered to be an off-label use of the drug.
Anzemet® (dolasetron mesylate) is a prescription medication approved for the prevention or treatment of nausea and vomiting due to surgery, as well as for the prevention of nausea and vomiting due to chemotherapy.
Surgery is a common cause of nausea and vomiting. However, not all types of surgery are likely to cause nausea and vomiting. Surgeries involving the abdomen (stomach area), eye, ears, nose, and throat are most likely to cause nausea or vomiting. Certain types of anesthesia are also more likely to cause nausea and vomiting. People who are at higher risk for postoperative nausea and vomiting include the following:
- People who have had nausea or vomiting after surgery in the past
- People who do not smoke
- People who get motion sickness
- People who will use certain morphine-like medications ("opioids") after surgery.
Your healthcare provider will take all of these factors into consideration when deciding whether you will need medication to prevent nausea and vomiting.
Anzemet is given before surgery to help prevent nausea and vomiting. Anzemet tablets are not approved to treat nausea and vomiting after it starts, and it is much harder to treat nausea or vomiting than to prevent it from happening in the first place. However, Anzemet injection is approved to treat nausea and vomiting after surgery.
Only Anzemet injection (not the tablets) is approved for this use. It can be used during surgery shortly before the end of anesthesia to help prevent nausea and vomiting. It if isn't given during surgery, it can be given any time after surgery to treat nausea.