Important Information for Your Healthcare Provider
Talk with your healthcare provider prior to taking this medication if you have:
- Kidney disease, such as kidney failure (renal failure)
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Had severe bone marrow depression (very low red blood cells, white blood cells, or platelets)
- Nerve damage or a disorder of the nervous system (the brain and nerves)
- Ever had a seizure
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Hexalen and Pregnancy)
- Breastfeeding (see Hexalen and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Altretamine to learn more, including information on who should not take the drug.)
In clinical studies, altretamine was given to women with ovarian cancer who had previously been treated with chemotherapy medicine combinations, including cisplatin (Platinol®) or medicines in the same class as altretamine (other alkylating agents). In these studies, 18 percent of women had either a complete or partial response to altretamine. The response lasted anywhere from 2 months to 36 months.