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Aloxi and Breastfeeding

Since no human studies have been conducted on the link between Aloxi and breastfeeding, it is not known whether the drug passes through breast milk. Some animal studies suggest that the medicine may increase the risk of tumors. Therefore, you should watch for any side effects in your infant if you are taking Aloxi and breastfeeding at the same time.

Aloxi and Breastfeeding: An Overview

It is unknown if Aloxi® (palonosetron hydrochloride) passes through breast milk in women. Consequently, it is also not known if Aloxi is safe for women who are breastfeeding. The manufacturer of the drug does not recommend breastfeeding while taking it.

What Does the Research Say?

No studies have been conducted on whether Aloxi passes through breast milk in humans. In addition, it is not known if Aloxi would cause any problems in breastfed infants. If your healthcare provider recommends that you take Aloxi while breastfeeding, be sure to watch for any side effects in your infant.
There is some concern due to a study in rats that suggests Aloxi may increase the risk of tumors, and exposing a young infant to a medication that may increase this risk should be avoided, if possible.
You may be wondering why no studies have been done to see if Aloxi passes through breast milk. In many situations, such studies would be considered unethical. Such studies might put infants at risk (who cannot themselves consent to these studies). In general, most information about breastfeeding and medications is obtained through cases outside of formal clinical studies.
Because Aloxi is long-acting, it is not feasible to "pump and dump" breast milk after a dose of Aloxi. The medication stays in your system for at least a week after each dose.
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Aloxi Drug Information

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