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Precautions and Warnings With Aldesleukin

Who Should Not Use Aldesleukin?

You should not use aldesleukin if you:
  • Had an abnormal heart stress test.
  • Had abnormal pulmonary (lung) function tests.
  • Had an organ transplant.
  • Had certain serious side effects with previous aldesleukin treatment, such as:
    • Heart rate or rhythm problems that were difficult to control
    • Chest pain (angina) or a heart attack
    • The need for intubation for over 72 hours (three days)
    • A serious condition known as cardiac tamponade (when excess fluid around the heart prevents the heart from functioning properly)
    • Kidney failure requiring dialysis for over 72 hours (three days)
    • Loss of contact with reality or severe confusion (psychosis) for over 48 hours (two days)
    • Coma
    • Seizures that were difficult to control
    • A hole in the intestines
    • Abdominal (stomach) or intestinal bleeding requiring surgery.
  • Are allergic to Proleukin, aldesleukin, interleukin-2, or any of the inactive components used to make the medication. Your healthcare provider or pharmacist has a list of the inactive ingredients.

Final Thoughts

There are a number of situations in which aldesleukin should not be used, along with several warnings and precautions people should be aware of before beginning treatment. However, it is possible that not all of these issues were discussed in this article. Therefore, you should talk with your healthcare provider about the specific safety concerns that may apply to you.
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