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Aldesleukin Side Effects

It is fairly common for people who are undergoing chemotherapy treatment with aldesleukin to develop side effects. Some of the most commonly reported problems include nausea, vomiting, and diarrhea. This drug can also cause potentially serious complications, such as low blood pressure or breathing problems, which may require immediate medical treatment.

An Introduction to Side Effects of Aldesleukin

Just like any chemotherapy medicine, aldesleukin (Proleukin®) can cause side effects, which can occur frequently and be quite significant. Talk to your healthcare provider about ways to prevent or manage adverse reactions during treatment.
(This article covers many, but not all, of the possible side effects with aldesleukin. Your healthcare provider can discuss a more complete list with you.)

Serious Aldesleukin Side Effects

Some side effects of aldesleukin are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
    • Dizziness
    • Lightheadedness
    • Fainting
  • Chest pain (angina) or pressure
  • Redness, blistering, flaking, or peeling of the skin
  • Unusual bleeding or bruising (see Blood Clotting Problems and Chemotherapy)
  • Black, tarry, or bloody stools
  • Vomiting blood or vomit that looks like coffee grounds
  • Persistent vomiting or diarrhea
  • Reduced urination or an inability to urinate
  • An irregular, rapid, or pounding heartbeat
  • Swelling of the arms, hands, legs, ankles, or feet
  • Difficulty breathing, shortness of breath, or a new or worsening cough
  • Sores or ulcers in the mouth or throat (see Mouth and Gum Problems During Chemotherapy)
  • Yellowing of the skin or whites of the eyes
  • Signs of anemia, such as:
  • Signs of infection, such as:
  • Pain, redness, irritation, or swelling at the site of the injection
  • Mood changes, such as depression or irritability
  • Confusion or difficulty thinking
  • Difficulty speaking or walking
  • Vision changes, such as loss of vision
  • Seizures
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing.
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Aldesleukin Drug Information

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