Cancer Channel
Related Channels

Drug Interactions With Abiraterone

Drug Interactions With Abiraterone Explained

The following sections explain in detail the potentially negative reactions that can occur when abiraterone is combined with any of the drugs listed above.
Abiraterone may increase blood levels of atomoxetine, potentially increasing the risk for side effects. If you take these medicines together, your healthcare provider may need to adjust your atomoxetine dose, especially when you first start or stop taking abiraterone.
Abiraterone can increase blood levels of carvedilol. If you take these medicines together, your healthcare provider will likely monitor your blood pressure and heart rate, and adjust your carvedilol dose if needed.
Abiraterone can make clopidogrel less effective. In general, it is not recommended to use these medicines together.
Abiraterone can make codeine less effective at controlling pain. If you are taking abiraterone and need a pain reliever, your healthcare provider might consider giving you a pain medicine that does not contain codeine.
Abiraterone can increase colchicine blood levels, increasing your risk for potentially serious colchicine side effects. If you take these medications together, your healthcare provider may give you a lower colchicine dose. He or she will also likely monitor you closely for colchicine toxicity.
CYP 3A4 Inducer Medications
The liver breaks down abiraterone using enzymes known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Combining abiraterone with one of these CYP 3A4 inducers may decrease the level of abiraterone in your bloodstream, making it less effective. Your healthcare provider may need to monitor you more closely to make sure abiraterone is working if you take it with a CYP 3A4 inducer.
Your healthcare provider may recommend taking twice as much abiraterone (split into two doses per day) while you are taking certain strong CYP 3A4 inducers.
The Zen of Cancer Caregiving - Recharge Your Batteries!

Abiraterone Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2020 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.