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Abiraterone Side Effects

Common Side Effects

Abiraterone has been studied extensively in clinical trials. In these studies, one group of people received abiraterone, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
 
In these studies, the most common abiraterone side effects included:
 
  • Joint swelling and discomfort -- in up to 29.5 percent of people
  • Decreased blood potassium levels (hypokalemia) -- up to 28.0 percent
  • Fluid retention (edema), especially of the legs and feet -- up to 26.7 percent
  • Muscle aches, spasms, or stiffness -- up to 26.2 percent
  • Hot flushes -- up to 19.0 percent
  • Diarrhea -- up to 17.6 percent
  • Urinary tract infection (UTI) -- up to 11.5 percent
  • Cough -- up to 10.6 percent
  • Increased blood pressure (hypertension) -- up to 8.5 percent
  • Increased urination -- up to 7.2 percent
  • Irregular heartbeat (arrhythmia) -- up to 7.2 percent.
 
Other common side effects, occurring in 2.3 to 6.2 percent of people, included:
 
  • An urgency to urinate during the night (nocturia)
  • Indigestion or heartburn
  • Cold-like symptoms
  • Chest pain (angina) or discomfort
  • Heart failure.
 

Final Thoughts

You may experience some or none of the abiraterone side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking abiraterone or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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